The ophthalmology practice of Dr. Mareen Schmidt & Dr. Sebastian Schmidt in the heart of Frankfurt Westend is your center of excellence for the diagnosis and treatment of severe retinal diseases. The Intravitreal Surgical Drug Administration (IVOM), Widely known as "eye injections," this procedure is the foundation of modern therapy for combating vision loss. Dr. Mareen Schmidt and Dr. Sebastian Schmidt, as experienced retinal specialists, understand the concerns associated with this procedure and have tailored the entire treatment process to their needs. patient-centered 5S method optimized to ensure maximum safety, comfort, and effectiveness.
Wet Age-Related Macular Degeneration (AMD): The most common indication. In this case, IVOM inhibits the growth and activity of abnormal blood vessels (neovascularization) beneath the retina, which destroy the central photoreceptors.
Diabetic macular edema (DME): This is a serious complication of diabetes and the most common cause of vision loss in people with diabetes. IVOM reduces the chronic swelling of the macula caused by vascular permeability.
Macular Edema Following Retinal Vein Occlusion: Following a venous occlusion (similar to a „thrombosis“ in the eye), IVOM combats the severe swelling and the resulting oxygen deprivation in the retina.
Inflammation inside the eye (uveitis): In certain cases, IVOM can be used to specifically control severe, non-infectious inflammatory reactions, often with the use of depot corticosteroid preparations.
The need for an intravitreal injection (IVOM) to treat conditions such as Macular degeneration (AMD), Treating diabetic macular edema or vascular occlusions requires the utmost precision and trust. As your Ophthalmologists in Frankfurt are Dr. Mareen Schmidt & Dr. Sebastian Schmidt specializing in precisely this therapy.
Based on her many years of experience as a senior surgeon and his extensive expertise from managing his own eye centers, they perform treatments with the utmost care and according to the highest hygiene standards. In their joint practice, you receive diagnostics, consultation, and IVOM therapy all under one roof, ensuring safe and continuous care for the long-term preservation of your vision.
We guarantee highest medical safetyEvery IVOM procedure is personally performed by Dr. Mareen Schmidt or Dr. Sebastian Schmidt. The extensive experience and expertise of our two retinal specialists are key to successful treatment. We consciously create a calm and trusting atmosphere. The entire procedure is performed with the utmost care and precision to ensure your comfort.
Thanks to intensive, multi-stage local anesthesia using highly effective eye drops, the procedure proceeds smoothly. low pain – You usually don't feel the injection, at most a brief, slight feeling of pressure.
We hold Uncompromising hygiene standards according to strict surgical guidelines This is to reduce the risk of infection – the most serious potential complication – to an absolute minimum. From the initial consultation to the precise planning and execution of the injection, right through to individualized aftercare, every step of the treatment is carefully monitored and documented by us.
You will receive detailed information. Before the procedure, your eye will be prepared by administering several doses of numbing eye drops until the surface is completely numb.
The eye and the surrounding skin are carefully disinfected, and the procedure is performed under the strictest sterile conditions to eliminate any risk of infection.
A gentle eyelid retractor keeps your eye open so you don't have to blink. Dr. Schmidt then administers the injection quickly, precisely, and safely into the white part of the eye.
Immediately after the injection, we check your intraocular pressure and visual function. Further follow-up care then takes place in the familiar setting of our office.
Drug (example) | Mechanism of action / special feature | Typical areas of application |
|---|---|---|
Lucentis® (ranibizumab) | VEGF-A blockade. A long history of proven effectiveness and a high safety profile. | Wet AMD, DME, vein occlusion. |
Eylea® (Aflibercept) | Acts as a „VEGF trap,“ binding VEGF-A and PlGF. Potentially longer intervals between doses are possible. | Wet AMD, DME, vein occlusion. |
Vabysmo® (faricimab) | Latest generation. Enables dual inhibition of VEGF-A and angiopoietin-2. | Wet AMD, DME. |
Ozurdex® (dexamethasone) | Cortisone depot implant. Strong anti-inflammatory effect lasting for months. | Uveitis, venous occlusion, refractory DME. |
Medications and Treatments for Retinal Diseases (IVOM)
Lucentis® (ranibizumab)
Mechanism of Action / Distinctive feature: Blockade of VEGF-A. A very long history of proven effectiveness and a high safety profile.
Typical indications: Wet AMD, diabetic macular edema (DME), venous occlusions.
Eylea® (Aflibercept)
Mechanism of Action / Special feature: Acts as a „VEGF trap,“ binding VEGF-A and PlGF (placental growth factor). Potentially longer duration of action is possible.
Typical indications: Wet AMD, diabetic macular edema (DME), venous occlusions.
Vabysmo® (Faricimab)
Mechanism of action / Distinctive feature: Latest generation. Enables dual blockade of VEGF-A and angiopoietin-2.
Typical indications: Wet AMD, diabetic macular edema (DME).
Ozurdex® (Dexamethasone)
Mechanism of Action / Special Feature: Cortisone-release implant. Strong anti-inflammatory effect lasting for months.
Typical indications: Uveitis (inflammation inside the eye), venous occlusions, treatment-resistant DMÖ (when other treatments are ineffective).
No. Thanks to the multi-stage, local anesthesia, you won't feel the actual injection. We make it a priority to ensure that your treatment is anxiety-free and comfortable.
IVOM is often a long-term treatment for a chronic condition. After an initial loading phase, the treatment intervals are individually adjusted based on your test results to achieve stable results with as few injections as possible.
IVOM is a very safe routine procedure when performed by an experienced specialist. Common but harmless side effects include minor bleeding on the surface of the eye or a temporary sensation of a foreign body. The most serious, but extremely rare, complication (infection) is minimized by maintaining the strictest sterile conditions.
No. On the day of your treatment, you must not drive yourself under any circumstances, as your vision will be temporarily impaired. Please arrange for someone to accompany you or take a taxi home.
Without consistent IVOM treatment, conditions such as wet AMD or diabetic macular edema typically progress. This leads to increasing and often irreversible damage to the retina and severe loss of central vision.
Yes, IVOM is a recognized treatment for eligible conditions and is fully covered by private health insurance companies.
Performing an IVOM procedure requires the utmost precision and expertise. As retinal specialists, Dr. Mareen Schmidt and Dr. Sebastian Schmidt possess the necessary expertise to guarantee you the safest and most effective treatment and to optimally manage the course of therapy.






Check-ups, laser medicine, interdisciplinary ophthalmology
Retina, macular therapy, laser medicine, prevention & more
Address for the GPS:
Grüneburgweg 95 (corner of Liebigstraße), 60323 Frankfurt am Main.
Parking recommendations:
We recommend the following parking garages in the immediate vicinity:
Palmengarten parking garage: (Entrance via Siesmayerstraße). From there, it's about a 5-7 minute walk to the practice.
Campus Westend parking garage: (Entrance via Theodor-W.-Adorno-Anlage). Perfectly located for reaching the practice on foot in just a few minutes.
By bus (line 75):
Use the Bus route 75 and get off at the stop Eppsteiner Straße From there, it's only about a 2-3 minute walk (approx. 200 meters) along Grüneburgweg to the practice at the corner of Liebigstraße. Alternatively, you can use the bus stop. University Campus Westend to use.
By subway (U6 / U7):
Drive to the station Westend. Take the exit towards Feuerbachstraße/Liebigstraße. If you follow Liebigstraße straight ahead to the north, you will walk directly towards Villa Westend on Grüneburgweg (approx. 7-minute walk).
Alternative via the Palm Garden:
From the subway station Westend or the bus stop Palmengartenstrasse You can reach us after a short, pleasant walk past the Palm Garden.